Heat starting forward P.J. Tucker departed Miami's Eastern Conference finals game against the Boston Celtics in the third quarter on Thursday due to a left knee contusion.
The Heat announced a short time later that the 37-year-old veteran wouldn't return to Game 2 of the best-of-seven series.
Tucker had five points and four rebounds in 22 minutes before exiting.
Tucker contributed five points and six rebounds in 31 minutes during Miami's 118-107 victory in Game 1 on Tuesday.
Miami also played without point guard Kyle Lowry (left hamstring strain) for the eighth time in the past 10 games.
--Field Level Media